prevalence of fungal allergens in respiratory allergic patients in ahvaz city, southwest iran

نویسندگان

abdol hussein shakurnia department of immunology, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran

mohammad ali assarehzadegan department of immunology, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran; department of immunology, faculty of medicine, ahvaz jundishapur university of medical sciences, ahvaz, ir iran. tel: +98-6113332036, fax: +98-6113332036

akram amini khuzestan jahad daneshgahi medical center, ahvaz, ir iran

ghodratollah shakerinejad khuzestan jahad daneshgahi medical center, ahvaz, ir iran

چکیده

patients and methods in this cross sectional study, 295 volunteers with the signs and symptoms of allergic diseases who referred to the khuzestan jahad daneshgahi medical center in ahvaz during 2010 were investigated. all patients were subjected to skin prick test (spt) with common allergenic extracts. data were analyzed by spss-18 software using chi square test. results seventy subjects, comprising 23.7% of the study group had positive skin test to at least one of the fungal allergens. the prevalence rate of sensitivity to fungal allergens was as follow: cephalosporin 11.5%; mold mix 9.8%; penicillium mix 9.5%; alternaria mix 8.1%; and aspergillus 5.1%. mean total ige in patients with spt was significantly higher than in patients without any positive skin prick test (251 vs. 125 iu/ml, p = 0.001). there was no statistical difference in the prevalence of sensitization to these allergens between two sexes; whereas, 15-35 age groups had significantly higher rates of allergy to fungal allergens (p =0.047). conclusions fungal sensitization is a relatively common finding among patients with allergic rhinitis. elimination or reduction of mold exposure in allergic patients is of special consideration and measures to reduce environmental factors which facilitate mold growth and proliferation are very important. background fungi are ubiquitous in our environment and they are one of the important causes of allergic diseases. identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis. objectives the purpose of this study was to determine the prevalence of skin reactivity to common fungal allergens and total ige in patients with allergic rhinitis in ahvaz city.

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عنوان ژورنال:
jundishapur journal of microbiology

جلد ۶، شماره ۴، صفحات ۰-۰

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